JPS5753488A - 2-o and 5-o substituted 1,4;3,6- dianhydrohexitol mononitrate compound, manufacture and drug composition - Google Patents

2-o and 5-o substituted 1,4;3,6- dianhydrohexitol mononitrate compound, manufacture and drug composition

Info

Publication number
JPS5753488A
JPS5753488A JP56116322A JP11632281A JPS5753488A JP S5753488 A JPS5753488 A JP S5753488A JP 56116322 A JP56116322 A JP 56116322A JP 11632281 A JP11632281 A JP 11632281A JP S5753488 A JPS5753488 A JP S5753488A
Authority
JP
Japan
Prior art keywords
substituted
dianhydrohexitol
manufacture
drug composition
mononitrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56116322A
Other languages
English (en)
Japanese (ja)
Other versions
JPS637549B2 (en]
Inventor
Kuretsushinku Kurausu
Sundaa Chiyatajii Shiyuyamu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Willmar Schwabe GmbH and Co KG
Original Assignee
Dr Willmar Schwabe GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Willmar Schwabe GmbH and Co KG filed Critical Dr Willmar Schwabe GmbH and Co KG
Publication of JPS5753488A publication Critical patent/JPS5753488A/ja
Publication of JPS637549B2 publication Critical patent/JPS637549B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP56116322A 1980-07-25 1981-07-24 2-o and 5-o substituted 1,4;3,6- dianhydrohexitol mononitrate compound, manufacture and drug composition Granted JPS5753488A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3028289A DE3028289C2 (de) 1980-07-25 1980-07-25 2-O- und 5-O-substituierte 1.4;3.6-Dianhydro-hexit-mononitrate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen

Publications (2)

Publication Number Publication Date
JPS5753488A true JPS5753488A (en) 1982-03-30
JPS637549B2 JPS637549B2 (en]) 1988-02-17

Family

ID=6108129

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56116322A Granted JPS5753488A (en) 1980-07-25 1981-07-24 2-o and 5-o substituted 1,4;3,6- dianhydrohexitol mononitrate compound, manufacture and drug composition

Country Status (7)

Country Link
US (1) US4364953A (en])
EP (1) EP0044931B1 (en])
JP (1) JPS5753488A (en])
AT (1) ATE12643T1 (en])
CA (1) CA1184916A (en])
DE (1) DE3028289C2 (en])
ES (1) ES503920A0 (en])

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002526544A (ja) * 1998-10-07 2002-08-20 レイサー ソシエダッド アノニマ イソソルビドモノニトレートの誘導体及び耐性が低下した血管拡張剤としてのその使用
JP2011528691A (ja) * 2008-07-22 2011-11-24 ラセル、ソシエダッド、アノニマ 血管拡張活性を有する硝酸イソソルビド

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3248548A1 (de) * 1982-12-29 1984-07-05 Heinrich Mack Nachf., 7918 Illertissen Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPH01262171A (ja) * 1988-04-13 1989-10-19 Nec Corp プリンタ
EP2199294A1 (en) * 2008-12-19 2010-06-23 Lacer, S.A. New stereospecific method for the preparation of dioxa bicyclooctane nitrate compounds
KR20160018697A (ko) * 2013-06-12 2016-02-17 아처 다니엘 미드랜드 캄파니 2-하이드록시메틸-5-푸르푸랄(hmf)의 환원 산물 유래 디카바메이트 및 그 유도체의 합성
ES2826825T3 (es) 2015-03-27 2021-05-19 Symbionyx Pharmaceuticals Inc Composiciones y métodos para el tratamiento de la psoriasis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1027891A (en) * 1962-01-02 1966-04-27 Aspro Nicholas Ltd Esters of dianhydro-hexitols
GB1356374A (en) * 1971-04-29 1974-06-12 American Home Prod Mononitrate esters of 1,3 3,6-dianhydro-d-glucitol
US3886186A (en) * 1971-04-29 1975-05-27 American Home Prod Mononitrate esters of 1,4:3,6-dianhydro-d-glucitol
US4169152A (en) * 1977-10-31 1979-09-25 Ici Americas Inc. Isohexide and tetrahydrofuran ethers and their carbamates in method of bringing about relaxation of skeletal musculature
DE2903927C2 (de) * 1979-02-02 1981-03-12 Sanol Schwarz-Monheim Gmbh, 4019 Monheim Verfahren zur selektiven Herstellung von Isosorbid-5-nitrat

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002526544A (ja) * 1998-10-07 2002-08-20 レイサー ソシエダッド アノニマ イソソルビドモノニトレートの誘導体及び耐性が低下した血管拡張剤としてのその使用
JP2011528691A (ja) * 2008-07-22 2011-11-24 ラセル、ソシエダッド、アノニマ 血管拡張活性を有する硝酸イソソルビド

Also Published As

Publication number Publication date
JPS637549B2 (en]) 1988-02-17
EP0044931A1 (de) 1982-02-03
ES8403911A1 (es) 1984-04-16
US4364953A (en) 1982-12-21
DE3028289C2 (de) 1986-11-27
DE3028289A1 (de) 1982-02-25
ATE12643T1 (de) 1985-04-15
ES503920A0 (es) 1984-04-16
EP0044931B1 (de) 1985-04-10
CA1184916A (en) 1985-04-02

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